The USB drivers for Galaxy Note 10.1 are automatically installed if you have installed Kies on your Windows computer. However, sometimes, while flashing custom or official ROMs, you might face difficulty in getting your Note 10.1 recognized by the computer.
To counter this problem, kill the Kies’ process from the task manager (ctrl+shift+esc) and install these official Samsung USB driver for your Galaxy Note 10.1. Download link. Install them the way you install any other windows application.